pentobarbital will lessen the level or effect of nilotinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
benzhydrocodone/acetaminophen and pentobarbital both raise sedation. Prevent or Use Alternate Drug. Limit use to individuals for whom option treatment method choices are inadequate
pentobarbital will lessen the level or result of alosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
pentobarbital will lessen the extent or impact of estropipate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will reduce the level or result of nelfinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will lessen the level or influence of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lower the extent or influence of isradipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unidentified.
Keep an eye on Intently (two)pentobarbital will lessen the level or impact of oliceridine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. If coadministration that has a CYP3A4 inducer is important, consider growing oliceridine dose until stable drug effects are realized; observe for indications of opioid withdrawal.
pentobarbital will reduce the level or outcome of prednisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lessen the extent or impact of osilodrostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or impact of vinorelbine by impacting hepatic/intestinal check here enzyme CYP3A4 metabolism. Minimal/Importance Unknown.
Keep track of Intently (1)pentobarbital will decrease the extent or impact of benzhydrocodone/acetaminophen by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Warning when discontinuing CYP3A4 inducers which can be coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone may perhaps boost and may lead to potentially deadly respiratory despair.
pentobarbital will reduce the level or influence of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. The efficacy of hormonal contraceptives could be minimized. Use of a nonhormonal contraceptive is suggested.
Phenobarbital lowers the plasma amounts of dicumarol (title Earlier made use of: bishydroxycoumarin) and causes a reduce in anticoagulant activity as measured because of the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing enhanced metabolism and lessened anticoagulant reaction of oral anticoagulants (e.